BMP-7: dosing and use context
Human schedule
Controlled data on this compound are limited. The regimens below were gathered from public sources online (studies and protocols) and are given as a reference, not a usage plan.
BMP-7 (recombinant bone morphogenetic protein-7) is used in studies not as a routine injectable peptide but locally: by intra-articular injection or surgical implantation on a collagen carrier. No systemic (subcutaneous) human regimen is established.
This is a concise reference to regimens described for adults; it is not an individual prescription.
| Period / condition | Dose | Escalation |
|---|---|---|
| Phase 1, knee (intra-articular, single dose) | 0.1 mg | Starting dose |
| Phase 1, higher level (intra-articular, single dose) | 0.3 mg | Increase if needed |
| Surgical implant (OP-1, on collagen, local) | 3.5 mg | Maximum in this schedule |
| Preclinical systemic reference (animal) | 30 mcg/kg, twice weekly | , |