RESEARCH USE ONLY
#доклінічні дослідження
Monographs tagged “доклінічні дослідження”.
ERR agonistsSLU-PP-332 — synthetic pan-ERR agonist (exercise mimetic)SLU-PP-332 is a synthetic small-molecule pan-ERR agonist (ERRα/β/γ) that, in rodents, reproduces part of the metabolic response to aerobic exercise (an «exercise mimetic»). It is a small molecule, not a peptide, and has no established human dose. This is a scientific reference summary for research-use-only (RUO) material.ERR agonistsSLU-PP-915 — an orally bioavailable, boronic-acid pan-ERR agonistSLU-PP-915 is a boronic-acid small molecule and pan-ERRα/β/γ agonist from Saint Louis University. Unlike the acylhydrazone SLU-PP-332, it was engineered for metabolic stability — and became the first orally bioavailable member of the series. The entire evidence base is cells and mice; there are no human studies.