RESEARCH USE ONLY
#дослідницький пептид
Monographs tagged “дослідницький пептид”.
Anti-fibrosisB7-33: a single-chain relaxin B-chain analog and functionally selective RXFP1 agonistB7-33 is a synthetic single-chain peptide derived from the relaxin-2 B-chain and the first functionally selective (biased) agonist of RXFP1, with anti-fibrotic activity in preclinical heart, lung and kidney models. This material is a scientific reference only (RUO); no established human dose exists.Mitochondrial & Longevity PeptidesMOTS-c (mitochondrial-derived peptide)MOTS-c is a 16-amino-acid peptide encoded within an alternative reading frame of the 12S rRNA gene (MT-RNR1) of mitochondrial DNA. It activates AMPK, translocates to the nucleus under metabolic stress and regulates adaptive gene expression; in preclinical models it modulates glucose and lipid homeostasis. The material is for laboratory research use only (RUO).Incretin AgonistsCagrilintide (AM833) — a long-acting amylin analogueCagrilintide (AM833, NN0174-0833) is a rationally engineered, lipidated analogue of human amylin (IAPP) with a once-weekly activity profile. This monograph covers its chemistry, mechanism of calcitonin/AMY receptor activation, the preclinical and clinical research record, pharmacokinetics and analytical characterization. Prepared strictly for research use only (RUO).