RESEARCH USE ONLY
#метаболізм
Monographs tagged “метаболізм”.
Mitochondrial & Longevity PeptidesMOTS-c (mitochondrial-derived peptide)MOTS-c is a 16-amino-acid peptide encoded within an alternative reading frame of the 12S rRNA gene (MT-RNR1) of mitochondrial DNA. It activates AMPK, translocates to the nucleus under metabolic stress and regulates adaptive gene expression; in preclinical models it modulates glucose and lipid homeostasis. The material is for laboratory research use only (RUO).Mitochondrial & Longevity PeptidesNAD⁺ (Nicotinamide Adenine Dinucleotide)NAD⁺ is the central redox coenzyme and, at the same time, a substrate for sirtuins, PARPs and CD38. An overview of its structure, biosynthesis (de novo, Preiss–Handler, salvage), redox chemistry, consuming enzymes and role in ageing biology. Research-use-only (RUO) reagent.ERR agonistsSLU-PP-332 — synthetic pan-ERR agonist (exercise mimetic)SLU-PP-332 is a synthetic small-molecule pan-ERR agonist (ERRα/β/γ) that, in rodents, reproduces part of the metabolic response to aerobic exercise (an «exercise mimetic»). It is a small molecule, not a peptide, and has no established human dose. This is a scientific reference summary for research-use-only (RUO) material.NAD+ / metabolic longevityNicotinamide Riboside (NR)Nicotinamide riboside is the riboside form of vitamin B3 and an NAD⁺ precursor with its own enzymatic route (NRK1/NRK2), described only in 2004. Mechanism, the 2025 enterohepatic-circulation finding, the NR-versus-NMN argument, and the central fact of the clinical record: NAD⁺ rises reliably, functional outcomes mostly do not. Research reagent (RUO).