RESEARCH USE ONLY

#RAMP

Monographs tagged “RAMP”.

Incretin AgonistsCagrilintide (AM833) — a long-acting amylin analogueCagrilintide (AM833, NN0174-0833) is a rationally engineered, lipidated analogue of human amylin (IAPP) with a once-weekly activity profile. This monograph covers its chemistry, mechanism of calcitonin/AMY receptor activation, the preclinical and clinical research record, pharmacokinetics and analytical characterization. Prepared strictly for research use only (RUO).