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RESEARCH USE ONLY

#biased agonism

Monographs tagged “biased agonism”.

Anti-fibrosisB7-33: a single-chain relaxin B-chain analog and functionally selective RXFP1 agonistB7-33 is a synthetic single-chain peptide derived from the relaxin-2 B-chain and the first functionally selective (biased) agonist of RXFP1, with anti-fibrotic activity in preclinical heart, lung and kidney models. This material is a scientific reference only (RUO); no established human dose exists.