RESEARCH USE ONLY
Bioregulators and Antioxidants
This hub covers research compounds that function as bioregulators and antioxidant reagents in laboratory studies. The collection includes reduced glutathione (GSH), a tripeptide with established roles in cellular redox chemistry, and Pinealon (Glu-Asp-Arg), a short peptide derived from Havinson research. These reagents are widely used in in vitro and in vivo research models to investigate oxidative stress, cellular signaling, and regulatory pathways.
In this topic
Bioregulators & AntioxidantsGlutathione (reduced, GSH)Glutathione (GSH) is the endogenous thiol tripeptide γ-L-glutamyl-L-cysteinylglycine, the cell's principal low-molecular-weight antioxidant and redox buffer. As an RUO reagent it is used to study redox homeostasis, xenobiotic detoxification, enzyme kinetics, and cellular models of oxidative stress.Bioregulators & AntioxidantsPinealon (Glu-Asp-Arg, EDR) — a Khavinson short peptidePinealon is a synthetic Glu-Asp-Arg (EDR) tripeptide from the Khavinson family of short peptides, studied as a neurotropic bioregulator. In preclinical models EDR penetrates the cell nucleus, interacts site-specifically with double-stranded DNA and modulates gene expression while lowering reactive oxygen species. This monograph summarizes its chemistry, molecular mechanism and the published research record; for research use only (RUO).