CJC-1295 with DAC: healthy-adult study regimens
> Updated:
Human schedule
CJC-1295 with DAC is given subcutaneously; albumin binding extends its half-life to ~6–8 days, so regimens are described as once-weekly dosing. The figures below are a generalized reference drawn from published pharmacokinetic data and protocols.
This is a concise reference to regimens described for adults; it is not an individual prescription.
People search CJC-1295 DAC dosing mostly to understand why the schedule is once weekly instead of daily like most growth-hormone research peptides. The pharmacokinetics below is the answer.
| Period / condition | Dose | Escalation |
|---|---|---|
| Start | 1 mg (1000 mcg) subcutaneously, once weekly | Starting dose |
| Maintenance | 2 mg once weekly | Increase if needed |
| Split regimen | 2 mg per week, divided into 2 injections (1 mg each) | Maximum in this schedule |
A full review of the mechanism and clinical data is available in the monograph.
Practical dosage and effect notes
In a trial by Teichman and colleagues (Journal of Clinical Endocrinology & Metabolism, 2006), healthy adults aged 21–61 received a single subcutaneous injection of CJC-1295 at 30 or 60 mcg/kg. Growth hormone levels rose 2- to 10-fold and stayed elevated for at least 6 days, while IGF-I rose 1.5- to 3-fold and stayed elevated for 9–11 days after just one injection; the authors described tolerability at both dose levels as satisfactory.
That directly explains why the schedule on this page describes once-weekly dosing rather than daily: if a single shot's effect lasts up to 11 days, a weekly interval sustains the level without excess buildup. The split regimen (2 mg weekly as two 1 mg injections) is a practical option for anyone uncomfortable with one larger volume, not a change in pharmacokinetics.
This is background for planning a research protocol, not a medical recommendation and not instructions for self-administration.
This reference is research-use material. The information is not medical advice and is not intended for diagnosis, treatment or prevention of disease.