MIF-1: dosing and reconstitution
Human schedule
MIF-1 (Pro-Leu-Gly-NH2) was given by subcutaneous injection in the available studies. The figures below are a generalized reference from published pilot protocols, not an instruction.
This is a concise reference to regimens described for adults; it is not an individual prescription.
| Period / condition | Dose | Escalation |
|---|---|---|
| Base cycle (day 1–5) | 10 mg subcutaneously, once daily, 5 consecutive days | Starting dose |
| Repeat cycle | 10 mg/day × 5 days after a 2-day to 1–2-week washout | , |
| Higher doses | 75 mg/day orally in some reports gave a weaker effect than the low dose | Maximum in this schedule (inverted-U curve) |