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PT-141 (Bremelanotide): reference dosing schedule

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Human schedule

PT-141 (bremelanotide) is given subcutaneously on demand, a single dose ahead of an event rather than as a course. Generalized from clinical studies (RECONNECT) and the label of the approved product Vyleesi.

This is a concise reference to regimens described for adults; it is not an individual prescription.

Period / conditionDoseEscalation
Starting (to gauge tolerability)0.5–1 mg subcutaneously, on demand, ≥45 min before the eventStarting dose
Studied regimen (Vyleesi)1.75 mg subcutaneously, single dose on demandIncrease if needed
Frequency limitno more than 1 dose per 24 h; up to 8 doses per monthMaximum in this schedule