5-Amino-1MQ dosing schedule
> Updated:
Human schedule
5-Amino-1MQ, as sold on this site, is supplied as a lyophilized powder for reconstitution with bacteriostatic water and subcutaneous injection. The figures below are a generalized reference drawn from preclinical data and described research protocols specifically for this route of administration.
This is a concise reference to regimens described for adults; it is not an individual prescription.
5-Amino-1MQ dosing in most described protocols starts at the low end and escalates gradually within a single 8-week cycle rather than holding one fixed dose for the whole period.
| Period / condition | Dose | Escalation |
|---|---|---|
| Start | 2.5 mg once daily, subcutaneous | Starting dose |
| Main regimen | 5 mg once daily (or 2.5 mg twice daily) | Increase if needed |
| Upper bound | up to 5 mg twice daily (~10 mg/day) | Maximum in this schedule |
| Cycle | 8 weeks on, then 4 weeks off | , |
Do not confuse this with the oral protocol. Open sources for 5-Amino-1MQ also describe a much higher dose, 50–150 mg/day, but that applies to a DIFFERENT product format, oral capsules, not the injectable powder sold here. The two regimens are not interchangeable: applying the oral dose to the injectable form would mean a many-times overdose.
Practical dosing and effect details
In a study by Neelakantan and colleagues (Biochemical Pharmacology, 2018), diet-induced obese mice received 5-Amino-1MQ subcutaneously three times a day at 20 mg/kg for 11 days. Over that period the animals lost about 5.1% of body weight, while control mice on the same diet gained about 1.4%; food intake did not differ between groups, pointing to a metabolic shift rather than appetite suppression. Fat tissue mass (epididymal fat) in the treated mice dropped by roughly 35% compared with controls. These results come from mice given systemic doses every few hours, not the once- or twice-daily injection shown in the schedule on this page; that difference is why research protocols for humans extrapolate a much lower daily dose split across fewer administrations. This is reference information for planning a research protocol, not a medical recommendation and not instructions for self-administration.
This reference is research-use material. The information is not medical advice and is not intended for diagnosis, treatment or prevention of disease.