5-Amino-1MQ dosing schedule
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Calculate the 5-Amino-1MQ dose
The calculator is already set up for 5-Amino-1MQ — adjust the dose or diluent volume for your vial.
Human dosing
| Period / condition | Dose | Escalation |
|---|---|---|
| Start | 2.5 mg once daily, subcutaneous | Starting dose |
| Main regimen | 5 mg once daily (or 2.5 mg twice daily) | Increase if needed |
| Upper bound | up to 5 mg twice daily (~10 mg/day) | Maximum in this schedule |
| Cycle | 8 weeks on, then 4 weeks off | , |
Do not confuse this with the oral protocol. Open sources for 5-Amino-1MQ also describe a much higher dose, 50–150 mg/day, but that applies to a DIFFERENT product format, oral capsules, not the injectable powder sold here. The two regimens are not interchangeable: applying the oral dose to the injectable form would mean a many-times overdose.
Practical dosing and effect details
In a study by Neelakantan and colleagues (Biochemical Pharmacology, 2018), diet-induced obese mice received 5-Amino-1MQ subcutaneously three times a day at 20 mg/kg for 11 days. Over that period the animals lost about 5.1% of body weight, while control mice on the same diet gained about 1.4%; food intake did not differ between groups, pointing to a metabolic shift rather than appetite suppression. Fat tissue mass (epididymal fat) in the treated mice dropped by roughly 35% compared with controls. These results come from mice given systemic doses every few hours, not the once- or twice-daily injection shown in the schedule on this page; that difference is why research protocols for humans extrapolate a much lower daily dose split across fewer administrations. This is reference information for planning a research protocol, not a medical recommendation and not instructions for self-administration.
How to reconstitute
An example reconstitution for convenient dosing. The exact ratios depend on your vial. For research reference only — not medical guidance.
- 1Add the diluentUse bacteriostatic water. Example: 2 ml into a 10 mg vial.5-Amino-1MQ10 mg+ 2 mlDiluent
- 2Get the concentrationExample: 10 mg in 2 ml =5-Amino-1MQ5 mg/ml(5,000 mcg/ml)
- 3Work out the volume per doseFor example, for a 2.5 mg dose:2.5 mg = 0.5 ml= 50 u. (U-100)
This is only an example calculation. You can use a different diluent volume — plug your own numbers into the calculator. Open calculator →
Research protocols
5-Amino-1MQ: reference regimens
5-Amino-1MQ, as sold on this site, is supplied as a lyophilized powder for reconstitution with bacteriostatic water and subcutaneous injection.
5-Amino-1MQ dosing in most described protocols starts at the low end and escalates gradually within a single 8-week cycle rather than holding one fixed dose for the whole period.
More scientific background in the 5-Amino-1MQ monograph
Notes and safety
- • 5-Amino-1MQ is a research peptide. Human safety and efficacy data are limited.
- • The regimens shown are based on publications and research protocols, not clinical recommendations.
- • Individual reactions may vary. Published protocols typically start dosing at the lower end of the reported range.
- • Not recommended for use with chronic illness, pregnancy, or breastfeeding.
- • This information is for educational purposes and is not medical advice.
