5-Amino-1MQ
5-Amino-1MQ
The batch you'll receive
Batch: B-2026-5AM1MQ-50-002
Lab: North American Diagnostics
Purity: >99.97%
Test date: 25.07.2026
View this batch's certificate of analysisAbout
5-Amino-1MQ is one of the most widely used tools for studying the role of NNMT (nicotinamide N-methyltransferase) in energy metabolism and adipose tissue biology. By inhibiting NNMT, researchers raise the intracellular NAD⁺ pool in adipocytes and study how that shift affects fat-cell differentiation, lipid handling and fat accumulation — which is why this compound has become a go-to reagent in obesity and metabolic-syndrome models.
Supplied as a white to off-white lyophilized powder in a sealed glass vial. Every batch is quality-controlled by HPLC, and the result is stated in the batch certificate. The material is intended for handling in a laboratory setting by qualified personnel.
The full scientific detail — mechanism of action, structure and links to the primary literature — lives in the linked wiki monograph. This page deliberately keeps to the practical characteristics of the reagent.
Store in a dry place away from light; freezing is recommended for long-term storage, and it is good practice to let the powder reach room temperature before opening the vial.
Specifications
Q&A
What is the half-life of 5-Amino-1MQ?
The half-life of 5-Amino-1MQ in humans has not been determined — no human pharmacokinetic study exists. The only published study is in rats: a half-life of 3.8 ± 1.1 h intravenously and 6.9 ± 1.2 h orally. Extrapolating those figures to humans is not defensible. See the Dosing section for detail.
DosingDosing
No validated human regimen has been established; available data are preclinical.
Full dosing guideTitration schedule · reference
