Glutathione dosing schedule
> Updated:
Human schedule
In studies and clinical protocols glutathione is given by injection, intramuscular or subcutaneous, and also intravenously (infusion). The figures below are a reference generalized from published studies and practitioner protocols, not an officially approved regimen.
This is a concise reference to regimens described for adults; it is not an individual prescription.
Glutathione dosing instructions in studies and practitioner protocols describe several administration routes and their dose ranges, so the glutathione schedule below is a reference point drawn from those sources, not an officially approved instruction leaflet.
| Period / condition | Dose | Escalation |
|---|---|---|
| Start (IM or SubQ) | 200–600 mg, 1–2x weekly | Starting dose |
| Maintenance (IM or SubQ) | 600–1200 mg weekly, split over 2–3 injections | Increase if needed |
| IV infusion (described in studies) | 500–1400 mg, 2–3x weekly | Maximum in this schedule |
Practical dosing and effect details
Glutathione is a tripeptide that is poorly absorbed when taken orally: digestive-tract enzymes, gamma-glutamyltransferase among them, break it down before absorption. Research protocols work around that barrier with injection or infusion, which is why this page lists three variants at once. IM or SubQ administration in smaller doses (200-1200 mg weekly, split across several injections) is described for maintaining a steady level; IV infusion in larger single doses (500-1400 mg) is described where the protocol calls for less frequent visits. Which route a published source uses is more often a matter of protocol convenience than a fundamental difference in how the compound acts: IV infusion is more often described under clinical supervision, while IM or SubQ dosing shows up outside a clinic too. This is reference information for planning a research protocol, not a medical recommendation and not instructions for self-administration.
This reference is research-use material. The information is not medical advice and is not intended for diagnosis, treatment or prevention of disease.