Glutathione
Glutathione
About
Glutathione (GSH) is a reduced thiol tripeptide and one of the principal intracellular antioxidants. Its free thiol (–SH) group makes it a common reference reagent in redox biology, oxidative-stress studies, and cell-culture work.
Supplied as a dry, white lyophilized powder. Every lot is checked by HPLC; typical purity is ≥98–99%, giving the consistency needed for reproducible experiments. Exact per-lot analytical values are listed in the accompanying certificate of analysis (COA).
The full scientific detail — mechanism of action, tripeptide structure, and physico-chemical constants — lives in the dedicated article in our wiki, linked from this page.
Store protected from light and moisture; a freezer is recommended for long-term storage. The reduced form is sensitive to oxidation, so minimise unnecessary exposure to air.
For research use only (RUO). Not a medicinal product; not intended for human or animal use, diagnostics, or any clinical application.
Q&A
What is the half-life of Glutathione?
The half-life of glutathione depends on the route. Intravenously it is approximately 10–14 minutes (two independent human studies). Orally there is no definable half-life — a single dose does not meaningfully raise plasma glutathione — so no single figure describes "glutathione" as such. See the Dosing section for detail.
DosingDosing
An adult study compared two daily oral regimens.
Full dosing guideTitration schedule · referenceReviews
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