HGH Fragment 176-191

In short: HGH Fragment 176-191 on the Longeva hub is a research sample of the C-terminal fragment of human growth hormone (somatotropin), supplied as a lyophilized powder with research use only (RUO) status. It is not a finished pharmaceutical product and not a dietary supplement, only raw material for laboratory protocols.

HGH Fragment 176-191 vs AOD-9604: are they the same?

Search queries for "HGH Fragment 176-191" and "AOD-9604" often treat the two names as interchangeable, though structurally they are not the same molecule. AOD-9604 is a separate, stabilized compound with an added N-terminal tyrosine (Tyr-fragment 176-191), sold by some suppliers under its own name. This page lists the unmodified C-terminal fragment of growth hormone (amino acids 176-191), not AOD-9604. The distinction, and what the research on both forms actually found, is covered in the blog review.

Research context: lipolysis without a glucose effect

The full growth hormone molecule drives both lipolysis (fat breakdown) and tissue growth, and also raises glucose and IGF-1 levels. In preclinical models, fragment 176-191 reproduced the lipolytic action through beta-3 adrenergic receptors, without the hyperglycemic and growth-stimulating effects that come with the full molecule. Several placebo-controlled human trials found the compound well tolerated with no serious adverse events, though these studies did not confirm a consistent, clinically meaningful reduction in body weight. The full reference list and a detailed walk-through of the preclinical and clinical data are in the HGH Fragment 176-191 wiki entry.

Sample format

Lyophilized powder in a glass vial, 5 mg fill. Store dry, cool, and protected from light per your lab's own SOP. Log receiving conditions, reconstitution, and subsequent storage in your internal batch record; the general research dosing protocol is described separately in the dosing reference.

Verifying a batch by COA

1. Find the LOT number on the vial and the outer packaging.
2. Open the PDF for this substance in the COA archive.
3. Check the substance name, the assay methods (HPLC, identity), and the result units.
4. Record the receiving date and the PDF link in your batch log.

COAs are issued by independent third-party labs; a report confirms the analytics at the time of testing, not the medical status of the material.

Further reading

Reference material. Not medical advice. This sample is intended for laboratory research use only (RUO). AOD-9604 refers to a separate compound and is not a product sold under that name on this page.