MOTS-c
MOTS-c
About
MOTS-c is a short mitochondrial-derived peptide (16 amino acids) tied to AMPK activation and the regulation of cellular energy metabolism. It holds a prominent place among subjects in metabolic biology and appears regularly in work on exercise physiology, cellular stress response and mitochondrial signalling.
The reagent ships as a lyophilized powder in a glass vial. Every batch is verified by HPLC, with typical purity of ≥98–99%, making it suitable for reproducible in vitro experiments. Batch paperwork (COA) is available to check against the lot number.
The full scientific write-up — mechanism, structure and primary-source references — lives in a dedicated wiki monograph linked from this page. Store the vial dry and protected from light; once reconstituted, follow standard peptide-handling practice.
Specifications
Q&A
What is the half-life of MOTS-c?
No half-life for MOTS-c has been established in any species — no pharmacokinetic study exists in humans or animals. No figure with a traceable primary source has been published. MOTS-c is encoded by mitochondrial DNA and produced endogenously, so a half-life is not cleanly definable for it even in principle. See the Dosing section for detail.
DosingDosing
No validated human regimen has been established; human interventional data are unavailable.
Full dosing guideTitration schedule · reference

